Indications & Dosage

Indications:

Conditions where the anti-inflammatory and immunosuppressive effects of the corticosteroids are desirable, especially for the intensive treatment during shorter periods.

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Dosage and Administration

This preparation on can be given directly from the vial without mixing or dilution. Solutions used for Intravenous or further dilution of this product should be preservative-free when used in neonate, especially for premature infant. If it will add to infusion solution, the mixture must be used within 24 hours since infusion solutions do not contain preservatives. Dosage may vary from 0.5 mg to 20 mg per day depending on the specific disease entity being treated. Usually, the parenteral dose is one third to one half of the oral dose, given every twelve hours. In certain overwhelming, acute life-threatening situations, dosages exceeding the usual recommended dosage have been used. In the circumstances, the slower rate of absorption by intramuscular administration should be recognized. Dosage requirements are variable and must be individualized on the basis of the disease under the treatment and the response of the patient. If the drug is to be stopped after it has been given for a few days, it is recommended that it be withdrawn gradually than stopped abruptly. In emergencies, the usual dose is 1 ml to 5 mL (4 mg to 20 mg) I.V or I.M. (in shock use only the I.V. route). This dose may be repeated un l adequate response is noted. After initial improvement, single doses of 0.5 to 1 mL should be repeated if necessary. The total daily dosage usually does not exceed 20 mL (80 mg), even in severe conditions. When constant maximal effect is desired, dosage must be repeated at three-hour or four-hour intervals, or maintained by slow intravenous drip. Intravenous and intramuscular injection are advised in acute illness. When the stage is passed, substitute oral therapy as soon as possible.
It can be administered intravenously, intramuscularly, intra-articularly and intrabursally or as prescribe by the physician.