Indications & Dosage

Indications:

Gentamicin Injection is indicated in the treatment of serious infections caused by susceptible strains of the following microorganisms. Pseudomonas aeruginosa, Proteus species (indole-positive and indole-negative), Escherichia coli, Klebsiella-Enterobacter-Serratia species, Citrobacter species, and Staphylococcus species (coagulase-positive and coagulase-negative).

Dosage and Administration

It is administered intramuscularly and intravenously in a single dose of 80mg/2ml. This dosage must be administered to patients weighing more than 50kg. The duration of treatment is determined by the physician.

Intramuscular Administration:
Adults: 3 mg/kg bodymass per day, one third being given every 8 hours. In life-threatening infections the dosage may be increased, to a maximum of 5 mg/kg bodymass daily, in three equally divided doses.

Children up to two years: 2 – 2,5 mg/kg bodymass every 8 hours.

Neonates (with severe infection): 6 mg/kg bodymass daily, divided into two or three equally spaced doses

Intravenous Administration:
The recommended doses for intravenous administration are the same as those used intramuscularly. Intravenous administration may be carried out slowly over 3 minutes or may be infused over a period of 20 to 30 minutes up to 2 hours.