Each vial contains Cefuroxime (as sodium)……………….750mg
Glass vial with halogenated rubber stopper and aluminum plastic combination flip-off cap + 10mL Type I colorless ampoule (Water for Injection as diluent) in a box.
Indications & Dosage
(Please check insert for indications)
Dosage and Administration
Cefuroxime sodium may be given by IM or deep slow IV injection over 3 – 5 minutes, or by IV infusion.
Adult: The usual dose is 750mg every 8 hours but in more severe infections 1.5g may be given intravenously every 8 to 6 hours. Parenteral doses may need to be reduced in renal failure. The suggested usual adult dose of 750mg should only be given twice daily when the creatinine clearance is between 10 and 20mL per minute and once daily when it is below 10mL per minute. Patients undergoing haemodialysis should receive additional 750mg dose following each dialysis.
Infants and Children: Doses can be given 30 to 60mg per kg body-weight daily increased to 100mg per kg daily if necessary, given in 3 or 4 divided doses.
Neonates: Doses can be given 30 to 60mg per kg body weight, increased to 100mg per kg daily in 2 or 3 divided doses. For the treatment of meningitis due to sensitive strains of bacteria, cefuroxime is administered intravenously in doses of 3g every 8 hours. Infants and children are given 200 to 240mg per kg daily intravenously in 3 or 4 divided doses, which may be decreased to 100mg per kg daily after 3 days or when there is clinical improvement.
For neonates, a dose of 100mg per kg daily, decreased to 50mg per kg daily when indicated, has been recommended. In the treatment of gonorrhoea a single dose of 1.5g by intramuscular injection, divided between 2 injection sites, has been suggested. A single 1g oral dose of cefuroxime has been given for uncomplicated gonorrhea. In each case an oral dose of probenecid 1g may be administered in conjunction with cefuroxime. For surgical infection prophylaxis the usual dose is 1.5g of cefuroxime intravenously prior to the procedure followed by 750mg intravenously or intramuscularly every 8 hours for up to 24 to 48 hours. For total joint replacement 1.5g of cefuroxime powder may be mixed with the methylmethacrylate cement. OR AS PRESCRIBED BY THE PHYSICIAN
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